Distinct chromosome abnormality patterns for differential diagnosis of hepatocellular carcinoma and cholangiocarcinoma
Fig 6
HCC and CCA cases were validated using the FISH technique.
(A) HCC case showed a negative result for 1p36 loss or gain with normal nuclei containing two orange and two green signals. (B) HCC case displayed a gain of 1p36 indicated by three orange and two green signals. (C) CCA case exhibited a loss of 1p36 characterized by one orange signal and two green signals. (D-F) Proliferative hepatocytes cases with normal nuclei. (G-I) Cholangitis cases with normal nuclei.