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Distinct chromosome abnormality patterns for differential diagnosis of hepatocellular carcinoma and cholangiocarcinoma

Fig 4

Identification of HCC and CCA chromosome abnormality regions.

(A) A principal component (PC) scores plot of HCC and CCA patients. (B) The PC analysis of HCC and CCA. (C) A heatmap clustering chromosome region marker. The x-axis represents cases of HCC and CCA. The y-axis represents different chromosome region markers. Z scored log2 ratio are shown from -2 to 2. Red indicates chromosome gain and blue indicates chromosome loss.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0322408.g004