Integration of bioinformatics and identification of the role of m6A genes in NAFLD
Fig 5
Key Genes Screening and LASSO Risk Model Construction.
A. The number of genes with the lowest error rate obtained by SVM algorithm. B. The number of genes with the highest accuracy obtained by the SVM algorithm. C. Diagnostic model diagram of LASSO regression model. D. Variable trajectory plot of LASSO regression model. E. Forest plot of key genes in LASSO regression model. F. Nomogram of key genes in NAFLD diagnostic model based on NAFLD dataset. G. Decision curve analysis (DCA) plot of key genes of nonalcoholic fatty liver disease (NAFLD) diagnostic model based on NAFLD dataset. H. Nomogram of key genes in non-alcoholic fatty liver disease (NAFLD) diagnosis model based on dataset GSE135251. I. Decision curve analysis (DCA) plot of key genes of non-alcoholic fatty liver disease (NAFLD) diagnostic model based on dataset GSE135251. SVM: Support Vector Machine. M6a-rdegs: m6A related differentially expressed genes, NAFLD: Nonalcoholic fatty liver disease, LASSO, Least Absolute Shrinkage and Selection Operator.