Noninvasive prognostication of hepatocellular carcinoma based on cell-free DNA methylation
Fig 2
Functional analysis of DNA methylation markers and cfDNA-based methRisk performance.
(A) Composition of markers in terms of genome annotation. (B) KEGG pathway enrichment analysis, and GO enrichment analysis of biological pathways associated with the methylation marker-related genes. The bar charts show the top 10 enriched terms ranked by p-value. (C) Time-dependent AUCs for individual features predicting 3-year survival in the patient cohort with plasma samples. Error bars represent the 95% confidence intervals. The sample size (n) is annotated to the right of the error bar.