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Trillin protects against doxorubicin-induced cardiotoxicity through regulating Nrf2/HO-1 signaling pathway

Fig 5

Trillin attenuated DOX-induced oxidative stress.

(A-D) CAT, GSH, SOD, and MDA lvels in cardiac tissue of mice. (E-H) CAT, GSH, SOD, and MDA levels in H9c2 cells (n = 6). ##P < 0.01 vs control; * P < 0.05, **P < 0.01 vs DOX.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0321546.g005