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Trillin protects against doxorubicin-induced cardiotoxicity through regulating Nrf2/HO-1 signaling pathway

Fig 2

Trillin improved DOX-induced cardiac dysfunction in C57 mice.

(A) Schematic protocol for DOX and trillin treatment. (B-G) Echocardiography parameters of HR, LVEF, LVFS, SV, LVIDs, and LVIDd in mice (n = 8). #P < 0.05, ##P < 0.01 vs control; * P < 0.05, vs DOX.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0321546.g002