Allosteric modulation of Plasmodium falciparum Isoleucyl tRNA synthetase by South African natural compounds
Fig 2
Potential orthosteric and allosteric pockets in PfIleRS and HsIleRS, and their predicted druggability attributes.
(A) PfIleRS orthosteric and allosteric pockets. (B) HsIleRS orthosteric and allosteric pockets. (C) Table of quality assessment parameters for each predicted pocket in PfIleRS: SiteScore, Size, DScore, Volume, Hydrophobicity, and Hydrophilicity. (D) Table of quality assessment parameters for each predicted pocket in HsIleRS.