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Beyond antibodies: Beta-2 glycoprotein I as the unsung guardian of pregnancy

Fig 2

Effects of progesterone on hepatocyte cells.

Twenty-four hours after the treatment with 17β-estradiol (E2) and progesterone (P), total-β2GPI levels (n = 4) and the relative levels of reduced-β2GPI (n = 4) in culture supernatants (n = 4) were assessed in HepG2 cells. All bars represent the mean ± SEM. Dot plots for each measurement value were superimposed onto the bar graph. Data were evaluated by one-way ANOVA (a) or Kruskal-Wallis ANOVA on Ranks (b) with Shapiro–Wilk normality test and Brown–Forsythe test, followed by Student-Newman-Keuls multiple comparison test.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0321405.g002