Characterization of the atypical antipsychotic drug aripiprazole cytotoxicity in the neutrophil model cell line HL-60
Fig 5
Dopamine receptor antagonists fail to inhibit aripiprazole-mediated loss of cell viability.
dHL-60 cells were treated with 20 μM of the dopamine receptor antagonist olanzapine, flupentixol, or eticlopride in the absence or presence of aripiprazole for 48 hours in media containing 2% serum. The average absorbance relative to DMSO control was graphed from at least three replicates. Error bars indicate the standard error of the mean. * indicates statistical significance via ANOVA with Tukey’s post-hoc test.