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Epsin bioactive coating reduced in-stent intimal hyperplasia by promoting early phase reendothelialization and inhibiting smooth muscle cell proliferation

Fig 5

Transfection efficiency, surface characteristics.

(A) A scanning electron microscope results showed surface of bare-metal stents and a collagen layer of shEpsin1 + siEpsin2 stents. (B) photographed from a confocal laser scanning microscope, cells on the stent were transfected. DAPI stained nuclei of the ECs on stent were blue and shRNA-transfected cells were green. Scale bars are 500µm SEM and water contact angle analysis. (C) and (D) Representative images of water contact angle testing on different surfaces. (E) Activated partial thromboplastin time (APTT) and prothrombin time (PT) measurements.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0318019.g005