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Computational screening and molecular docking of compounds from Traditional Chinese Medicine (TCM) by targeting DNA topoisomerase I to design potential anticancer drugs

Fig 2

The molecular dynamics simulations study of the DNA topoisomerase I.

a) the root mean square deviations, b) solvent accessible surface area, c) hydrogen bond, d) radius of gyrations, e) the root mean square fluctuations of the complexes.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0310364.g002