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A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model

Fig 1

Flowchart of the experimental design.

ONC, optic nerve crush; BMD, brimonidine; QD, once daily; BID, twice daily.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0308671.g001