New antibacterial candidates against Acinetobacter baumannii discovered by in silico-driven chemogenomics repurposing
Fig 2
Biofilm formation and tavaborole effect on mature biofilm of five Acinetobacter baumannii strains in polystyrene plates.
(A) Quantification of biofilm biomass formed after 48h incubation without the presence of the investigated drug determined through OD reading at 595 nm. Each symbol represents the mean of triplicates. (B) Percentage of OD reduction for biofilm biomass treated with 16 μg/ml tavaborole for 24h. (C) Metabolic activity reduction rate recorded for biofilm treated with 16 μg/ml tavaborole for 24h. The bars represent the mean and standard deviation of different experiments. Three independent experiments were performed.