Polyploid giant cancer cells induced by Docetaxel exhibit a senescence phenotype with the expression of stem cell markers in ovarian cancer cells
Fig 5
The SA-β-Gal activity was increased and the mitochondrial membrane potential was lost in PGCCs.
(A) SA-β-Gal staining to reveal the activity of β-galactosidase. Representative image was shown (magnification 10×20). Black arrows indicated the SA-β-Gal-positive cell. Bar = 100 μm. (B) JC-1 staining to reveal the mitochondrial membrane potential. Representative scatter plot was shown. Bar graphs showed the percentage of JC-1 monomeric form (n = 3). P values were calculated by One-way ANOVA. ***P<0.001 (vs. control).