Disturbance in the protein landscape of cochlear perilymph in an Alzheimer’s disease mouse model
Fig 5
Protein profiles of the perilymph and cerebrospinal fluid (CSF) in KI mice.
(A) Venn diagrams showing the numbers of up- or downregulated proteins in perilymph or CSF (left: upregulated, right: downregulated). (B and C) List and characterization of the quantitively changed proteins in the CSF of KI mice compared with that in WT mice. The names of up- or downregulated proteins are displayed in panel B. In panel C, the proteins are classified in terms of localization into five different categories according to the annotation in UniProt. The data are derived from the work of Jiang et al. [26].