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Raman difference spectroscopy and U-Net convolutional neural network for molecular analysis of cutaneous neurofibroma

Fig 3

Distinction of neurofibroma from other physiological entities via Raman spectroscopy and PCA.

(A) Mean purified spectra of cutaneous neurofibroma, physiological skin, fat, nerve, bone and mucosa, and the assignment of the Raman peaks to their respective molecular origin is shown in rectangular colorized boxes. (B) PCA with scatter plot of the projections of the purified Raman spectra of cutaneous neurofibroma, as well as physiological skin, fat, nerve, bone, and mucosa onto the first three principal components.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0302017.g003