Cyasterone has a protective effect on steroid-induced Osteonecrosis of the femoral head
Fig 6
Representative images of Micro-CT and HE staining, and the structural parameters of Micro-CT.
Fig 6 (A, B) showed the HE staining and Micro-CT reconstruction images of the three groups of rats; Fig 6A showed the results of Micro-CT after sampling of the femoral head of the three groups of rats; Fig 6B showed that the trabecular bone in the model group was obviously sparser and partially broken than in the Control group (Scale bar: 400 μm, the red arrow represents the necrotic area while the white arrow shows the normal area); The Fig 6C showed that the values of BV/TV, Conn.D and Tb.N increased in the Cyasterone group and the value of Tb.Sp decreased in the Cyasterone group. (The samples conformed to normal distribution and the variance was homogeneous, and one-way analysis of variance was used for comparison among multiple groups. *P<0.05, **P<0.01, Model group compared with Control group; #P<0.05, N = 5, Cyasterone group compared with model group).