The inflammatory response of human pancreatic cancer samples compared to normal controls
Fig 5
CNET plot showing gene overlaps in enriched genesets.
Geneset enrichment analysis of genes differentially expressed between tumor and normal samples indicated enrichment for sets of genes involved in KRAS signaling (purple), inflammatory response (turquoise), complement cascade (red), and epithelial mesenchymal transition (green). Black dashed circle indicates PLAUR, which connects to all four genesets. Genes at the end spokes indicate differential expressed in our dataset that were enriched in each geneset, color of dots indicated whether the gene was up (red tones) or down (blue tones) regulated in tumors relative to normal samples [17, 21, 35].