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Clinical sensitivity and specificity of a high-throughput microfluidic nano-immunoassay combined with capillary blood microsampling for the identification of anti-SARS-CoV-2 Spike IgG serostatus

Fig 5

Sensitivity and specificity comparison.

Sensitivity and specificity with 95% confidence interval are shown. Euroimmun ELISA and NIA index test were performed on serum obtained by venipuncture. Mitra, (glucose) test strips, and HemaXis correspond to the device used for capillary blood collection after fingerprick, and DBS-A to automated extraction of samples obtained on HemaXis. Capillary blood samples were dried, shipped, and extracted before testing on the NIA assay. A dotted line at 95% sensitivity or specificity is shown for visual aid.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0283149.g005