GATA-3 expression in breast cancer is related to intratumoral M2 macrophage infiltration and tumor differentiation
Fig 1
Breast cancer immunohistochemistry images.
Image A shows a tumor with GATA-3 positive cancer cells (nuclear staining marked with a red arrow). Image B illustrates a GATA-3 negative tumor where cell nuclei (blue arrow) show no GATA-3 staining. Images C-E show immunohistochemistry for M2-macrophage specific marker CD163 used for detecting M2-macrophages (red arrow) and scoring macrophage infiltration. Images C, D, and E illustrate No/low, moderate, and high macrophage infiltration, respectively.