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Identification of host genomic biomarkers from multiple transcriptomics datasets for diagnosis and therapies of SARS-CoV-2 infections

Fig 2

Cross-validation of DEGs by WGCNA.

(A) Illustration of soft-thresholding powers based on the scale-free tropology model fit (left) and the mean connectivity (right). (B) The dendrogram of all DEGs clustered based on a dissimilarity measure (1-TOM). (C) The dendrogram of eigengene module and cluster analysis of eigengene network by heatmap summarize the modules yielded in the clustering analysis. (D) Median rank preservation (left) and Z summary preservation (Right); the black, red, yellow and turquoise indicate the strong preservation above dashed lines Z = 2 and Z = 10.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0281981.g002