Assessment of oligoclonal bands in cerebrospinal fluid and serum of dogs with meningoencephalitis of unknown origin
Fig 5
Immunoblot with serum and CSF samples from five canine patients (nos. 1–5) and one human MS patient (no. 6) after isoelectric focusing.
Dog no. 1 was diagnosed with intracranial neoplasia, dog no. 2 and dog no. 3 with idiopathic epilepsy, dog no. 4 with MUO, and dog no. 5 with a disease outside the CNS. CSF-specific OCBs (equivalent to pattern 2 and 3 of the described patterns in human medicine; OCBs highlighted between arrowheads) were detected in dog no. 4. The samples from the human MS patient served as positive controls. CSF = cerebrospinal fluid, MS = multiple sclerosis, MUO = meningoencephalitis of unknown origin, CNS = central nervous system, OCBs = oligoclonal bands.