The trehalose glycolipid C18Brar promotes antibody and T-cell immune responses to Mannheimia haemolytica and Mycoplasma ovipneumoniae whole cell antigens in sheep
Fig 4
IgG antibody responses to M. ovipneumoniae antigen promoted by C18Brar adjuvant persist long-term.
Mean (+SE) serum IgG antibody responses to M. ovipneumoniae at 34 weeks after initial vaccination in animals vaccinated with either Antigens alone (Ags), antigens formulated with Quil-A (QA), Emulsigen-D (ED), Aldhydrogel + QuilA (AGA), or C18Brar. Antibody responses were measured in serum samples using ELISA. Significant differences are represented by * P = < 0.05 in antibody responses compared to Ags alone group. NS = non-significant.