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Mechanism of LH release after peripheral administration of kisspeptin in cattle

Fig 1

Experimental model used in Experiment 2.

Emergence of a new follicular wave (Day 0) was induced by follicular ablation (FA) three days after ovulation, and an intravaginal progesterone-releasing device (CIDR) was inserted immediately after follicle ablation and left in place for 13 days. Luteolytic doses of a prostaglandin F analog (cloprostenol) were given on Day 3.5 and 4. Ovarian ultrasonography was performed daily during the experiment. Blood collection and treatment administration was done on Day 6.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0278564.g001