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Sodium thiosulfate through preserving mitochondrial dynamics ameliorates oxidative stress induced renal apoptosis and ferroptosis in 5/6 nephrectomized rats with chronic kidney diseases

Fig 5

Histologic graphs from H&E stain (A, C) and Masson stain (B, D) were displayed in sham, CKD and STS treated CKD (CKD STS) rats. The increased leukocytes infiltration (yellow arrows) is indicated in the tubular area of the CKD kidney (A, C). Increased masson stain by blue color is indicated in the glomerular (B) and tubular areas (D) of the CKD kidneys. The mean data of number of leukocyte infiltration and % of blue Masson stain for each section is indicated in E and F, respectively. Data are expressed as mean ± SEM (n = 6). * P < 0.05 vs. Sham. # P < 0.05 vs. CKD. The eight Sham panels in Figures 5A-D are excluded from this article’s CC-BY license. See the accompanying retraction notice for more information.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0277652.g005