Effects of infectious disease consultation and antimicrobial stewardship program at a Japanese cancer center: An interrupted time-series analysis
Fig 5
Trends in the incidence of methicillin-resistant Staphylococcus aureus (MRSA) per 1000 patients, by month, during Phase 2 of the intervention period.
Each dot refers to the incidence of MRSA per 1000 patients each month and the slope is based on linear regression in the two phases. The explanation of each phase is as follows: Phase 1 (antimicrobial notification by the infection control team from April 1, 2018, to March 31, 2020); Phase 2 (establishing an infectious disease [ID] consultation service and implementation of the Antimicrobial Stewardship Program [ASP] from April 1, 2020, to March 31, 2021). The number of isolated samples in 2018, 2019, and 2020 was 61, 72, and 69, respectively. The level of the monthly incidence of MRSA did not decrease (coefficient: 0.12; 95% confidence interval [CI]: −0.16 to 0.42, p = 0.40), although there was a significant reduction in the trend of the infection (coefficient: −0.05; 95% CI: −0.09 to −0.013, p = 0.01).