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Kinetics and mechanisms of catalyzed dual-E (antithetic) controllers

Fig 24

Reaction schemes when E1 and E2 in a m4-type of control structure (Fig 3) are removed by enzyme Ez with two compulsory-order ternary-complex mechanism.

In (a) E1 binds first to Ez, while in (b) E2 binds first.

Fig 24

doi: https://doi.org/10.1371/journal.pone.0262371.g024