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Effects of psychogenic stress on some peripheral and central inflammatory markers in rats with the different level of excitability of the nervous system

Fig 5

Effect of long-term stress on neutrophil:lymphocyte ratio (N:L ratio) in LT and HT rats.

Intertrain comparison of intact rats (A), effect of stress on N:L ratio in HT strain (B), effect of stress on N:L ratio in LT strain (C), dynamics of stress related changes in N:L ratio in HT (D) and in LT rats (E). LT control–low excitability threshold, control group, LT stress–low excitability threshold, stressed animals; HT control–high excitability threshold, control group, HT stress–high excitability threshold, stressed animals; n = 9–11 per group; bars represent medians and interquartile range; B—** p≤ .01 (Mann-Whitney test), D-F **—p≤ .01 (Wilcoxon test with FDR correction).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0255380.g005