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pyProGA—A PyMOL plugin for protein residue network analysis

Fig 5

NDA predictions and experimental data.

The NDA scores for the residues in the UL141…TRAIL-R2 complex based on an FMO/DFTB calculation. The top panel shows the scores of residues in both proteins (the border is depicted by the dashed line) and the bottom is a detailed plot for the residues of the TRAIL-R2 protein. The table contains experimental SPR (surface plasmon resonance) data published elsewhere [87]. Specific site mutations in the TRAIL-R2 protein to alanine (so called alanine scan), resulted in altered stability of the complex. The NDA bars corresponding to the residues that were mutated in the SPR experiments are labelled.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0255167.g005