Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides
Fig 1
A) Isopeptide bond between glutamine and lysine formed by the action of the transglutaminase (TG) enzyme with release of ammonia. B) Isopeptide bond between glutamic acid (or aspartic acid) and lysine formed by exposure to organophosphorus chemicals (OP) with release of water. Figure adapted from [18].