Turnover rate of coenzyme A in mouse brain and liver
Fig 2
Level of unlabelled pantothenic acid (PA), free CoA (CoASH) and acetylCoA in A) female and B) male mouse liver and C) female and D) male brain after administration of a single oral dose of [13C3-15N]-PA. C57BL/6N mice were kept for 3 days under a PA-free diet and then orally dosed with 25 mg/kg of [13C3-15N]-PA. Liver and brain samples were harvested over a collection period of 0–342 h and unlabelled PA, CoASH and acetylCoA level were measured by LC-MS.