Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment—In vivo studies
Fig 5
Alterations in collagen deposition in response to cathelicidin (CRAMP) and/or Saline Extract of Pantoea Agglomerans (SE-PA) treatment.
Protein concentration was investigated in homogenates of lungs collected from untreated mice and animals exposed to investigated compounds for 14, 28 or 42 days using the ELISA method. The data are presented as a mean of protein concentration ± SEM. Each research group contained 8 mice: 6 treated and 2 untreated animals. Samples were collected from all animals and analyzed in 2 replications. (control mice N = 20; treated mice per research group N = 6). * p < 0.05 vs. untreated; # p < 0.05 SE-PA+CRAMP 14 d./28 d. vs. SE-PA 14 d./28 d. (comparison within corresponding time points); @ SE-PA 28 d. + untreated 14 d. vs. SE-PA 28 d.; $ p < 0.05 SE-PA 28 d. + CRAMP 14 d. vs. SE-PA 28 d. + untreated 14 d.; one-way ANOVA test; Tuckey post-hoc test.