Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment—In vivo studies
Fig 2
Changes in immune cells composition in response to cathelicidin (CRAMP) and/or Saline Extract of Pantoea Agglomerans (SE-PA) treatment.
Cells number was investigated in lungs collected from untreated mice and mice exposed to investigated compounds for 14, 28 or 42 days using flow cytometry. The data are presented as mean of cell number ± SEM. Each research group contained 8 mice: 6 treated and 2 untreated animals. Samples were collected from all animals and analyzed in 2 replications. (control mice N = 16; treated mice per research group N = 6). * p < 0.05 vs. untreated; # p < 0.05 SE-PA+CRAMP 14 d./28 d. vs. SE-PA 14 d./28 d. (comparison within corresponding time points); @ SE-PA 28 d. + untreated 14 d. vs. SE-PA 28 d.; $ p < 0.05 SE-PA 28 d. + CRAMP 14 d. vs. SE-PA 28 d. + untreated 14 d.; one-way ANOVA test; Tuckey post-hoc test.