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Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions

Fig 9

Mass spectrometry analysis of Ringers solution collected from the Ussing chambers (N = 4) during ex vivo recovery in the presence of A6 or LA.

A: Degradation of either LA or A6 during ex vivo recovery. The half-life of LA and A6 in ischemic injured jejunum tissue is 35 minutes and 78 minutes, respectively. B: A6 fragments A6F1, A6F2, and A6F4 are generated during the 240-minute ex vivo recovery. Values are means ± SEM; n = 4.

Fig 9

doi: https://doi.org/10.1371/journal.pone.0250165.g009