Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions
Fig 1
Electrophysiological responses and FITC-LPS flux quantification of ischemia-injured porcine jejunal mucosa to treatment with single doses of LA at various concentrations.
LA was added to the apical bathing solution after a 30-minute equilibration period to allow for stabilization of baseline electrical measurements (indicated by the arrow at 30-minutes). Statistical significance (* or **) is shown between ischemia-injured jejunal mucosa treated with 1 μM LA and untreated ischemia-injured jejunal mucosa. TER Values are means ± SEM; n ≥ 7 except for LA (0.1 μM) where n = 3. Total LPS flux values are means ± SEM; n ≥ 9.