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Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

Fig 8

Metformin concentrations in A—muscle and plasma at normal muscle volume (28L) and increased muscle volume 48L and B—adipose and plasma at normal adipose volume (15L) and increased adipose volume 75L.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0249594.g008