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Specimen-specific drift of densities defines distinct subclasses of extracellular vesicles from human whole saliva

Fig 2

Specimen-specific density drift.

(A) Western blotting for CD63 from specimen 1 (S.1), Specimen 2 (S.2) and Specimen 3 (S.3) both in the downward (D) and upward (U) centrifugation. A position of 48 KDa molecular weight marker is indicated at the right side of S.1 D panel, and the fraction numbers are indicated on the top. (B) The densities of 60 fractions from three specimens (Specimen 1 in blue, 2 in green and 3 in red) both in downward (circles) and in upward (squares) centrifugation are plotted, including those fractions with the strongest signals of CD63 (filled circles and squares).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0249526.g002