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Characterizing and quantifying the temporal relationship between structural and functional change in glaucoma

Fig 2

Examples of CCF plots of RA on MS for two patients included in this study.

The conventional CCF identified the strongest absolute correlation (tallest overall spike illustrated in red and green stripes the same as the strongest positive correlation) at lag = −4 (panel A) and +1 (panel B). The modified CCF identified the strongest positive correlation (tallest spike above the zero line) at lag = −4 (panel A, in red and green stripes because the same as the strongest absolute correlation) and +6 (panel B, illustrated in green). The dashed blue horizontal lines indicate statistical significance at the p = 0.05 level.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0249212.g002