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Cell competition between anaplastic thyroid cancer and normal thyroid follicular cells exerts reciprocal stress response defining tumor suppressive effects of normal epithelial tissue

Fig 5

Detection of phosphorylation of ERK1/2.

ACT1 cell clusters were co-cultured with GFP-NTECs for 5 days, fixed with formaldehyde, and stained with anti-phosphorylated ERK1/2 antibody (red) and anti-Ki-67 antibody (green). (A) Merged image. (B) Red fluorescence image showing regional phosphorylation of ERK1/2 in NTECs. The bar indicates 100 μm.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0249059.g005