Lung gene expression and single cell analyses reveal two subsets of idiopathic pulmonary fibrosis (IPF) patients associated with different pathogenic mechanisms
Fig 4
Gene signature scores for hematopoietic cell populations in GSE47460 (Kaminski-LGRC bulk expression cohort) [14–17] subclasses.
Signatures were determined using total lung mononuclear cell data from GSE132771 (Sheppard-UCSF single cell cohort) [19]. Cell cluster names follow labeling in S3A Fig. Labels used in S3A Fig are indicated in parentheses. A. Gene signature scores for B cell subpopulations. B. Gene signature scores for T cell populations. C. Gene signature scores for myeloid cell subpopulations. Adjusted p values are reported on plots.