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Data-driven CAD-CAM vs traditional total contact custom insoles: A novel quantitative-statistical framework for the evaluation of insoles offloading performance in diabetic foot

Fig 5

Sub-optimal offloading performance case.

Assessed R-ROIs (yellow squares) and the underfoot pressure redistribution (white squares) induced by the insoles obtained for one subject in the 3 considered conditions. Red squares are introduced, and they represent those cells that belong to R-ROIs, for which no statistical difference has been detected by the paired t-Test between pairs of conditions. The sequences of the panels and their meaning are the same as in Fig 4. In this case, the custom-made insoles either TCCI or CAD-CAM_CMI were not able to remove the determined R-ROIs in the FI condition altogether (see the values in the left top corner of the panels–left foot zoomed on the right side to highlight the differences in the R-ROIs surfaces). The recorded blueprints with related previously manually marked clinical at-risk locations (i.e. callosities and sites of previous ulcers) are superimposed on the FI related images. Reprinted under a CC BY license, with permission from Bioengineering & Biomedicine Company Srl, Pescara, Italy, original copyright 2020.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0247915.g005