Anti-CD19 CAR T cells potently redirected to kill solid tumor cells
Fig 4
CAR T cell activity in response to restimulation.
A) Extent of CAR T cell proliferation after 2 rounds and 4 rounds of Raji cell stimulation, SKOV3 cell restimulation or no stimulation; CAR T cell types are indicated below the x-axis. B) Extent of CAR T cell-mediated cytotoxicity against target tumor cells and 1 round and 3 rounds of Raji cell stimulation, SKOV3 cell restimulation or no stimulation. The round of stimulation, cell source of stimulation is indicated, and target cell in the cytotoxicity assay are indicated. * = p, 0.001. NS = no significant differences.