Hyper-connectivity between the left motor cortex and prefrontal cortex is associated with the severity of dysfunction of the descending pain modulatory system in fibromyalgia
Fig 2
Timeline assessments. CPM-test: condition pain modulation test; fNIRS: functional near-infrared spectroscopy. Pain VAS: Pain visual-analog scale. NPS: numeric pain scale. QST: Quantitative Sensory Testing. T0: mean temperature (three measurements per individual) at which the subjects reported a pain score of 6/10 on the NPS (0–10) during the QST before the heterotopic stimulus. T1: temperature equivalent to T0 but applied during hand water cold immersion. NPS(T0): NPS pain score during application of T0. NPS(T1): NPS pain score during application of T1.