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Avidin-biotin complex-based capture coating platform for universal Influenza virus immobilization and characterization

Fig 2

3D AFM topography images with corresponding 1D profiles through dashed lines as shown.

A) 460 μm sapphire c-cut slide. B) Capture coating on sapphire slide. C) Influenza A H3N2 virus cluster immobilized in capture coating on sapphire slide. The tendrils of the capture coating bPEG2kSA receptor tethers are clearly seen. D) A 2D example image of one of many single virions (this one Influenza A H3N2) immobilized in capture coating. 2DFFT analysis for all four AFM scans shown in S2 Fig.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0247429.g002