CYP4B1 is a prognostic biomarker and potential therapeutic target in lung adenocarcinoma
Fig 5
Differentially expressed genes correlated with CYP4B1 in LUAD.
(A) Volcano plot showing differentially expressed genes significantly associated with CYP4B1 (FDR<0.05; |Pearson’s r|>0.2). (B, C) Heatmaps showing the top 50 significant genes positively and negatively correlated with CYP4B1 in LUAD. (D-F) The top three significant genes demonstrating positive co-expression with CYP4B1 in LUAD. (D) Pearson correlation of CYP4B1 expression with PEBP4, C16orf89, and SFTPD. (E) The mRNA expression profiles of PEBP4, C16orf89, and SFTPD in LUAD tissues when compared with normal lung tissues. (F) Survival analysis of PEBP4, C16orf89, and SFTPD in LUAD. FDR, false discovery rate; LUAD, lung adenocarcinoma.