Visual properties of human retinal ganglion cells
Fig 6
Donated human retinas are healthy.
(A) Multi-electrode array layout (gray) and electrodes with sortable, light-responsive cells (green) of two example experiments. Responding cells are distributed across the recorded retinal pieces. (B) Distribution of peak firing rates in response to full-field contrast steps. (C1) Top: Number of cells responding at any given time point (gray bars) was similar to the total number that had responses until that time point (horizontal lines). Bottom: Mean ± standard deviation of peak firing rate for the responding cells. Data from a subset of experiments that lasted for 2.5h (N = 4 experiments, N = 52 cells). (C2) Example firing rate traces for one cell. (D) Spontaneous background firing rates (mean ± standard deviation) of the same cells and time points as in C1. (E) Number of responding units and ischemia time for donors without (black) and with (gray) known adverse condition (indicated in Table 1). (F) Number of responding cells for individual stimuli as a function of ischemia time. Lines indicate linear fits. (G) Total number of responding cells and responses per stimulus for donors with and without known adverse condition. Lines indicate median numbers.