Hemagglutination Inhibition (HAI) antibody landscapes after vaccination with H7Nx virus like particles
Fig 5
Protection against stringent H7N9 challenge.
C57BL/6 mice (8 mice/group) vaccinated with H7 VLPs at week 0 and 4 were intranasally infected with the A/Anhui/1/2013 H7N9) virus. Mice were monitored daily for weight loss (A and B, respectively) and viral lung titers in selected mice at day 4 post infection (C). Weight loss and lung viral titer was presented as mean± standard deviation (A and C). *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.