Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding
Fig 3
Luciferase reporter gene transcription activation assays.
Dose-response curves are shown for the assays for (A) ERα and (B) ERβ. E2 was used as an internal standard compound in the assays for ERα and ERβ. Log[chemicals (M)] is the logarithm of the concentration of test chemicals plotted on the X-axis.