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Stress and corticotropin releasing factor (CRF) promote necrotizing enterocolitis in a formula-fed neonatal rat model

Fig 2

Mucosal injury and NEC scoring system.

Representative H&E-stained terminal ileum sections to show mucosal injury consistent with NEC. (a) Normal intestinal mucosa: score 0. (b) Mild inflammation: score 1. (c) Moderate inflammation consistent with NEC: score 2. (d) Severe inflammation consistent with NEC: score 3.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0246412.g002