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A comparative study on the use of microscopy in pharmacology and cell biology research

Fig 2

Comparative analysis of the proportion of use of different optical and electron microscopy techniques in biomedical sciences journals.

We analyzed in each article the use of 8 types of optical microscopy techniques: bright field (BrF), phase contrast (Pha), differential interference contrast (DIC), polarization (Pol), conventional fluorescence (Flu), confocal fluorescence (Conf), super resolution (SRes), and live cell imaging (Live); and 3 types of electron microscopy techniques: transmission (TEM), scanning (SEM) and cryo-EM (CrEM). Data were collected from articles published in 2019 in the biomedical sciences journals: British Journal of Pharmacology (BJP), Journal of Pharmacy and Pharmacology (JPP), Frontiers in Pharmacology (FP), Journal of Cell Biology (JCB), Journal of Cell Science (JCS), Cells (CEL), Journal of Biological Chemistry (JBC) and Proceedings of the National Academy of Sciences (PNAS). N = 200 articles analyzed in each scientific journal.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0245795.g002